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Measure content performance. Develop and improve products. List of Partners vendors. Hoodia gordonii , or Bushman's hat, is a succulent herb from South Africa. Since the early s, it has been promoted as a safe and effective appetite suppressant useful for weight loss. Some alternative practitioners believe it can also treat indigestion and mild gastrointestinal infections.
It may have other medicinal properties as well. To date, though, there is little evidence backing any benefits of hoodia. This article looks at the research behind claims about hoodia, its possible dangers, how to use it, and what to look for when buying it.
For centuries, the nomadic San people of South Africa have gnawed on hoodia while traveling through the desert. They believe the succulent blocks hunger and boosts energy. By , the CSIR isolated a steroid sugar believed responsible. They named it P Nearly 20 years later, pharmaceutical giant Pfizer bought the rights to P They planned to make a weight-loss supplement but never did.
Pfizer then released the rights and other manufacturers started making P57 products. Interestingly, a review of studies said it takes a lot of hoodia to reduce appetite.
Authors also said that weight loss is actually a side effect of the herb. Today, numerous hoodia supplements are sold. Early research suggests Hoodia may do the following, but more research is needed:. Despite centuries' worth of use to suppress appetite and boost energy, hoodia has not been proven to be useful for these or any other purposes.
Hoodia is considered safe at low doses. However, at appetite-affecting doses it may cause:. Hoodia may also suppress thirst along with appetite. That raises concerns about dehydration. Components of the plant could raise liver enzymes and affect liver function. However, research has not found that it damages the liver.
People on diabetes drugs should be cautious with hoodia. It may cause dangerous drops in blood sugar. Due to the lack of research, hoodia should not be used:.
It's unknown whether hoodia causes any drug interactions. Laboratory studies suggest it inhibits an enzyme that helps your body use many medications. Talk to your healthcare provider and pharmacist about hoodia before you start taking it.
If you have unusual symptoms while taking hoodia, or your medications seem to become less effective, stop using hoodia and call your healthcare provider. The amount of hoodia it might take to have any weight-loss effect can cause side effects ranging from headache to rapid heart rate. Hoodia is not considered safe for everyone, and it may affect how well some medications are used in the body.
The women were allowed to eat as much as they wanted during their stay at the clinic, yet there was no difference in calorie intake or weight loss between the two groups. They experienced cases of side effects -- three times the number reported by women eating normal yogurt -- including headaches, nausea, vomiting and odd skin sensations.
They showed increases in pulse and blood pressure, and signs of liver damage. The Hoodia-based medication no longer in development is just one example of a long series of failed diet pills. Earlier this year, for example, U.
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